Une étude publiée dans Science Translational Medicine a trouvé un moyen de modifier le groupe sanguin de poumons destinés à la transplantation utilisant la perfusion ex vivo des poumons (EVLP), créant des organes de type sanguin universels. Cette découverte pourrait révolutionner la transplantation en améliorant l’équité dans l’attribution des organes.
« With the current matching system, wait times can be considerably longer for patients who need a transplant depending on their blood type, explains Dr. Marcelo Cypel, Surgical Director of the Ajmera Transplant Centre and the senior author of the study.
Having universal organs means we could eliminate the blood-matching barrier and prioritize patients by medical urgency, saving more lives and wasting less organs, adds Dr. Cypel, who is also a thoracic surgeon at UHN’s Sprott Department of Surgery, a Professor in the Department of Surgery at the University of Toronto and the Canada Research Chair in Lung Transplantation. »
